Proflavine Binding to Transfer Ribonucleic Acid, Synthetic Ribonucleic Acids, and Deoxyribonucleic Acid
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چکیده
منابع مشابه
Proflavine Binding to Transfer Ribonucleic Acid, Synthetic Ribonucleic Acids, and Deoxyribonucleic Acid*
The ability of proflavine to directly inhibit protein synthesis has led to an investigation of complex formation between the drug and ribonucleic acid. Evidence has been obtained from absorption and fluorescence spectra, as well as heat denaturation curves, that proflavine forms a complex with transfer ribonucleic acid which is qualitatively similar to the deoxyribonucleic acid-proflavine compl...
متن کاملProflavine binding to transfer ribonucleic acid, synthetic ribonucleic acids, and deoxyribonucleic acid.
The ability of proflavine to directly inhibit protein synthesis has led to an investigation of complex formation between the drug and ribonucleic acid. Evidence has been obtained from absorption and fluorescence spectra, as well as heat denaturation curves, that proflavine forms a complex with transfer ribonucleic acid which is qualitatively similar to the deoxyribonucleic acid-proflavine compl...
متن کاملThe Enzymatic Methylation of Ribonucleic Acid and Deoxyribonucleic Acid. Vii. the Methylation of Ribonucleic Acid.
Preceding publications from this laboratory have shown that the methylation of soluble ribonucleic acid is catalyzed by at least six discrete enzymes (l-3) which have been purified from extracts of Escherichia coli W. Two of these enzyme preparations catalyze the formation of l-methylguanine residues in SRNA,1 while a third produces 7-methylguanine. The others catalyze the methylation of uracil...
متن کاملAmino acids attached to transfer ribonucleic acid in vivo.
1. tRNA was extracted from rabbit liver by both the phenol and diethyl pyrocarbonate methods under conditions preventing deacylation of the amino acids attached in vivo. 2. After deacylation 12 amino acids were determined by gas-liquid chromatography, by using the flame-ionization and nitrogen-sensitive thermionic detectors. 3. Comparison of the distribution of 12 amino acids attached to tRNA w...
متن کاملThe Enzymatic Phosphorylation of Ribonucleic Acid and Deoxyribonucleic Acid
The specificity of the enzyme purified from TZ-infected Escherichia coli which catalyzes the phosphorylation of 5’hydroxyl ends of ribonucleic acid and deoxyribonucleic acid has been examined. The enzyme also catalyzes the phosphorylation of 5’-hydroxyl groups of polynucleotides as well as 3’-mononucleotides. There is no detectable phosphorylation of nucleosides and adenosine 2’-phosphate is vi...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1967
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)95814-x